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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65df2d920c34fcfc2d6f971a0b8c0eb2a20563d00bbbb85e14dc6b9aeb09042' 
  AND token = 'SkgkdxutsRExHG059cSh+sUIdGxCmo3HKXvWFwzNQ4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}