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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c73e3134d500bd525481913341387462cbed8d05a0598ae4f703283aab2ef10' 
  AND token = 'iP4JskLeuoExIkB5bH1A6MKIDt/IEWjbEYuWP8T9RvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}