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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45db9d9f254b68e32c950c683f1cadd65989659a84b64f721dfe233e661cdae2' 
  AND token = '2rYbLfLwlprKI0CYMelPHzU6MuMBPg6Gr+ACcg4Aci4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}