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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab116f3cd095e5e557219a2597d24c7c4ea1ce89b70a1382eea89a54bd3bc2d2' 
  AND token = '+E9PeFMNcjKeToVLTGDW051FIlNROXMh7MwKwOp5YDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}