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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7528636ef9d6cf9b61ea679d6e59dd57d6b9068e81fd4ba5d45b51a8d174aa28' 
  AND token = 'EsIVSj2RIbnSOvsqs364JCVn8d8aXJ8PO1TUay+i5XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}