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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0517cb9bca0b6d9e34a65f38957f0abadb01b946b3d9a6f2b21933ad1a3627' 
  AND token = 'TAqSLq5RpymCityAM08d/p1enKQRlE4tHfakwQhAb74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}