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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9200d0da393baa7a269bd240e1ee38c07cad2dff2537f5ed0749ce4792da11a' 
  AND token = 'vA2a6bTH0j3JpWFTtEpTkSuGAVSQftyZinqsDFaDMuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}