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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a02d5382d3a258629b48044e586a12e02bbad769bfb98b31b8ea9462dc0b8b' 
  AND token = 'UxHKm/K1rSB0fyW3cc90qoTG85WusQ21Q1ssz3ewtog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}