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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4326c67dc464b6c57b2f8037b64185200967e2d6fe82b78b90fdc3c9de0dbcea' 
  AND token = 'Z0M+4Ra0jVsXcfoTyTgDVRp3XhAh0N54zTyojARxYbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}