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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f1c6897d1039b88ac2ec6bf063cf1f4602360a4b835421e2c8d7d5a433bf59' 
  AND token = 'pR4sKVAQWzHPQHuvxdnAv3y/f2kF/4E0xw8zuCb3FFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}