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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b26e73dee58f2b4971f89bb6341769221458d9013d1f1c71bba7bd4c8b29cf' 
  AND token = 'qEF8Aqa9nTMDcrTNYI5800dBikepLYyNR6Rx9nWMJ0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}