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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '614fbcc0a63e21ee76b4494cca95e724184de26571e047aa1ec3e76935ff53f0' 
  AND token = 'Xb9g0jzTuHX1AmIR+31XhNBrFLrKW5mBBM4C0+xNg3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}