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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be60ee4ca401e39f0ea4de9112c06c68002db747a15fe6823c37f373348df9cd' 
  AND token = 'nvz8k8EhLn3eUuaa1B5gjmQcbvTF/fIrIfE+rt8MzHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}