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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fecd5483a01cd5aa948e46da1d1605243598bbb53514b8181d8d5bcb193c0cf' 
  AND token = 'DIuBsarX8d1dXRW01kJqAtEQf70gVMnViVoCNc12v0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}