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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ddaec3c0f00ab5566f66341880f2559ade4092891c30e27309ea8b572f9ee0' 
  AND token = 'vIRiXHrI2nlbA5T/lcZbMLjYRq8F2yDzzuLj/N4ZpCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}