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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e3c11fd79247dcf1483a8a0478dfc64caaa5794f90773b0fb2ff8976d5c410' 
  AND token = '88Yis7v7zJOHhtdJ56pt+675ZC8bHA86O4UazRiG+bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}