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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ab1ae9e1188c41fdde94ebf0518c7cae434ffab5cad01fe9891ba7c32d2403' 
  AND token = '1QTo47oEa2xk+pfBOgBi6bJyMR0vO0hDC01irUknoqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}