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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e748e165e0d3c4e91b3281b206469d6f9041e47504a60d70fda2616e4cd3871c' 
  AND token = 'SgolFtnn6sNqLOLDlbhX8f3ONXfmtCcGgZMFy+2DpW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}