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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed6fa679ff38ab9e5b08082559c68fcacf425d47cc858a9952ff2dd54b1ddfe' 
  AND token = 'HUFvU7gd+DD3eZx6gnJWBp+4tNOwW2MQyKe1tXXF8I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}