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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861593b529369c4906527598897e4fca827cd664aecd386686b58b4c9a4e3469' 
  AND token = 'I64QYW+SeBLOTj+h+n0zvc4qpi4Z2S0Nm/m9vD3XnlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}