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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f4575942675f51f900fe5a2d67a996297a88777f9dfd58eda38d8d95afbf8b2' 
  AND token = 'm4nFIpoCn4XA4ikmgA+aXETc3/4oAjlJ81FsX78ZUPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}