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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ecca799d135606ca213d0b5605f54eb9c14121b256ba2b3672eb1fa1ff575a' 
  AND token = 'xev8qL97lPTpDHVKWL2YF/rOKP2YLyUD/k3PlreE7yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}