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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257b1e396355d7b994a78dcd43e026eb49d174846f0cba404510f49833bfed44' 
  AND token = 'GT3FXdBr1WWgF0FCkWrW3oe6/IEve2J1YiEDLqcza3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}