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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc708d2ae9e2eeb17d5c5daa06c280b076c0f01539dca3c8e9c13371455248bb' 
  AND token = 'y/T0CMexzxGtRDp8qHW777HbfED7oplQMwDGIRFCR1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}