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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca6bb42a51eae028a377520db118358c729a6702dcc7142bb4df0337cb6fa000' 
  AND token = 'uwivEp016m31qPeA3FGdLOArsf1CqtmY17jRUtiU8v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}