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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d426cde7a1b311b61ce933030232f39cf4302cd760115792f159c05ea4ed0c5' 
  AND token = 'cNG+AjtE3u8t88f4mASe5ZNPS9Jw7kBT+njp2LW+/Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}