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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2253d7f14e9b2a5d254e8f7c3b1c2d70d9f3434dbb3a4becb1adeca8d09086b3' 
  AND token = 'loKjhhZTYM9L3/NAo6JIKEvFSgNm5mO5gxeXodfegoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}