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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03908f25944cbd32a3f28e9034c88641733a7f4b1a858e826f3216c845a4810' 
  AND token = 'IEu1/7j4Xgby9y3lQqXPq6PyoyhAPIuph/Lj9h9OqfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}