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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '959f928f0b2a460cd8a45962533a19e0641aaa12f1581468a956f4e0b71ebae3' 
  AND token = 'boIJK/SvSe2tmgANSoPxWddgY7VRtk99fR5HEKZ5Bgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}