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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f591c574fa5d86d92115d36cae5a0a22aba2d380080d377adbdd25d7a49af677' 
  AND token = 'pYgHST5N0kR7NzOcXDmR0kXwfjY/Swyxri4Wy2Z4U4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}