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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c7b0c61b31080071fb3cbbb6db4fb0f88011f16c32eff6d165fc5db689ccf77' 
  AND token = 'QnHyfrbO1L75N+9UGXK490w6GO6bjiXKTtCXG27IMxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}