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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04cd1b0b002a91f376a2c846b5a3d47b026bc08dc9779ca540df2037b5baaa2b' 
  AND token = 'AQWPivRSjnhkmBV3g7K8OCDHs8WCySrHisZWLg+QdUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}