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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74431196e52d875cdf06b001b86e671f527e8bc29acb555a901c6c5f113d89a' 
  AND token = '2qTEKI0Ufi2hjp0EKdCHX18mp8gC6fiMSX/0TaKduz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}