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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41131efd9df6c8e500c332e80ea0bf244587e9bb12c156ec2e96eefd2570eb95' 
  AND token = 'r4SNKSxKcVInyM4XzJWZaAKxN1NFQw+tV18ZAGhKvEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}