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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52da435568320cd2ea4ef11e68e91d682028fec500ee939467122794bf13a7a2' 
  AND token = 'aH4yFkxuIry/LAcLyYmz3IHQnD3ZizCDHq/vb4wr2jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}