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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3187757eab876c282079aced9b4e4feac152abc2a03aedeb03704a3e155d9661' 
  AND token = '5dQCf1EIDa7g2dk778D0SZ9B3VgcsA1ODOmOtMGmK3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}