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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e11e71164d574c45adad25d69368d908cce8b4b78e4e8f9a3d114ceca5e812' 
  AND token = 'MR8cSROEfBDr+z2wVDrFeMk8kSekUBV9Y/OazPCzALU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}