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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0ec061db13b65ddbada2be9f83b23ea13916a02516d8b95c71bfa8587cd98d' 
  AND token = 'Z7ubkthx5LeVQR+CcQKWCKXEGAaGwZ2PX0eVFYWi50Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}