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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f88ffdc000df30593de013892adad909887668b1ddd5b8170515f573b8369c0' 
  AND token = 'eH4xLKxxBP5Si/3Rb0QQWxzJtS38uwYPCoIJ8eDbTEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}