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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09d97ab11371ce120734d634ca324b410ae644214696332977012bc01c8d4546' 
  AND token = 'TYeov/kYcv8bQvuq+gxy3XXWcr9GTfEB4qvWKMTxC9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}