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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e0fe967800fc40f951fae2352bcd2c8d26ae0842358a58d8c69ad34b85501b' 
  AND token = '4lbHlDOM4JQVy5ezoHvKsa3EhVK0wfNZdOWkzJ9F1Vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}