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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83d14d92a1889e0242169eaf371614a991f8101d41697ff4629f988fbd5975f9' 
  AND token = '7RT9qtMlM1E+tZkkJvLsYK+O2uIvi4b1Dqbpy/lK5a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}