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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20165ce10d8b9d441e41c18553ca91196aa0e264e987347ba5f3c56abc814532' 
  AND token = 'A+r0ul5XNc2/nYFBhm7MmZdlacnxIuY2/GV8YlniFIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}