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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8f96ffba8103b1279bfade2aeff6f65faefc181836df73de193c7b23a1f391' 
  AND token = 'X8AyGTUpB7oJUBMX6gaOBBF4jnfVZe+HAfG10ejzUKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}