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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99be9808c2d3e9d94ae314e642c1efedb648a0c35143e0c6d2c093229fadbff8' 
  AND token = '3Zw2rJti0mJKOElAg2nSZt1AQOE814/3opF+a1hqr3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}