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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b07822ce73ccf16c28386863ae7e1f8c5964156fd56357cf2d5cf11eb51a446' 
  AND token = '9iYXMTz9GRSv9rMpY9scV+dklo5f5WoSGMNxAV1EEEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}