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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5bc252f844565e4bf029c1d9280d58162ccb4c0c652b248871325616a5d61cd' 
  AND token = 'oXHtI4S4Hk8RcFn1TCkbw2ZW8ohdUbCRsKOnQxdEqbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}