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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '509cace673ee3df3958c663ef27fae0eb2f596e4d312501e2c5af7b84a1a5136' 
  AND token = '6VeBFMGDdMQuxt7MPaFUEG/GMZxH3SyNugtlvLFwQlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}