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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b342c77c1cf332bebbd599a3dd8f45631c4591da730c6ab3cc517395dd21351' 
  AND token = '8ZaaQJIqT8k5X/aOROTG/RvSbxuJXp4/XMz4H8UCOLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}