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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff0e702bfc410d65a2d6adad3168150050011b690d3c3c54f73dea8cd072f25' 
  AND token = 'Ar2BO05DKWqIPEKKqahKPg/ZPhTSdC6lzbiBGTLnfTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}